Equilibrium and Kinetic Study of Bovine Serum Albumin (BSA) Adsorption onto Fabricated Polyethersulfone (PES)/Hydroxyapatite (HAP) Adsorptive Mixed Matrix Membrane (MMM)

To cite this article: Ahmad, A. L., Shoparwe, N. F. & Hanifa, N. H. E. (2019). Equilibrium and kinetic study of bovine serum albumin (BSA) adsorption onto fabricated polyethersulfone (PES)/hydroxyapatite (HAP) adsorptive mixed matrix membrane (MMM). J. Phys. Sci., 30(Supp. 1), 43–63, https://doi.org/10.21315/jps2019.30.s1.3


In this study, different amount of hydroxyapatite (HAP) was embedded into polyethersulfone (PES) matrix to prepare adsorptive mixed matrix membranes (MMMs). All fabricated membranes were characterised based on functional groups, morphology, overall porosity, water content, hydrophilicity and pure water flux. The relationship of equilibrium and kinetics of bovine serum albumin (BSA) adsorption onto fabricated membrane in a batch system was performed. The BSA adsorption equilibrium data is best described by Freundlich isotherm model followed by Langmuir isotherm model. The kinetics of the adsorption is well presented by pseudo-second-order kinetic model and followed by pseudo-first-order kinetic model. Among all membranes, fabricated PES/ HAP adsorptive MMM (K4) produced with 60 wt% HAP shows the best characteristic of membrane with higher water content, porosity and hydrophilicity, demonstrating the higher average pure water flux, jw of 29.12 m2 l–1 h–1 ± 0.6 m2 l–1 h–1, adsorption capacity, qe of 26.54 (g BSA.g membrane–1) and adsorption kinetic rate, k2 of 0.814 (h–1). The reusability of K4 membrane shows the most effective regeneration compare than other membrane. The results suggested that the PES/HAP adsorptive MMM can be effectively applied for the adsorption of BSA from aqueous solution and can offer high potential merit for application in membrane adsorption process.